| 15/04/2022 |  |
Stade RennaisStade Rennais | 2 | x | 3 | AS MonacoAS Monaco |  |
||
| 16/04/2022 |  |
Saint-ÉtienneSaint-Étienne | 2 | x | 1 | BrestBrest |  |
||
| 16/04/2022 |  |
LilleLille | 1 | x | 2 | LensLens |  |
||
| 17/04/2022 |  |
NiceNice | 2 | x | 1 | LorientLorient |  |
||
| 17/04/2022 |  |
MetzMetz | 1 | x | 1 | Clermont FootClermont |  |
||
| 17/04/2022 |  |
MontpellierMontpellier | 0 | x | 0 | Stade de ReimsReims |  |
||
| 17/04/2022 |  |
NantesNantes | 1 | x | 1 | AngersAngers |  |
||
| 17/04/2022 |  |
TroyesTroyes | 1 | x | 1 | StrasbourgStrasbourg |  |
||
| 17/04/2022 |  |
LyonLyon | 6 | x | 1 | BordeauxBordeaux |  |
||
| 17/04/2022 |  |
Paris Saint-GermainPSG | 2 | x | 1 | MarseilleMarseille |  |